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DermaLight ™ Skin Lightener Info


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  • Derived from flowers of Bellis perennis (Daisy Flower)
  • Highly efficient natural skin lightening by influencing different pathways involved in melanin formation
Influence on Melanogenesis Pathways


in vitroResults

Influence on Melanogenesis Pathways




Reduction of Endothelin



Blocking of MC-1 Receptor


α-MSH Binding Capacity


Influence on Melanogenesis Pathways



Determination of Tyrosinase Expression
Determination of Tyrosinase Expression1.2.3.




Influence on Tyrosinase Expression





Influence on Tyrosinase Activity
Reduction of Tyrosinase Activity


Influence on Melanogenesis Pathways

Influence on Melanogenesis Pathways


Endocytosis

Endocytosis

FluoSphereUptake (%)

Microscopic images showing the FluoSphere(red beads) uptake in control and in DermaLight™ treated human  keratinocytes.
For visualization of the endocytosis, cells were counterstained with DAPI (blue nuclei).

Endocytosis was stimulated by UV light.
Endocytotic Activity -FluoSphereUptake


Influence on Endocytotic Activity

Endocytotic Activity
FluoSphereUptake (%)

Endocytosis was induced with UV. The uptake of FluoSpheres was detected with a fluorescence reader at 582 nm / 612 nm.
Influence on Endocytotic Activity020406080100Control1%


 







 


INCI: Bellis perennis (Daisy) Blossom Extract

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